Long-Term Efficacy and Safety of Zonisamide Monotherapy in Epilepsy Patients

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منابع مشابه

Long-Term Efficacy and Safety of Zonisamide Monotherapy in Epilepsy Patients

BACKGROUND AND PURPOSE Zonisamide (ZNS) is a useful antiepileptic drug with a broad therapeutic spectrum. However, there is limited information on the long-term use of ZNS as a monotherapy. This study investigated the long-term effects of ZNS as a monotherapy for the treatment of epilepsy. METHODS We retrospectively analyzed the records of epilepsy patients treated with ZNS monotherapy at our...

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Clinical efficacy of zonisamide in childhood epilepsy after long-term treatment: a postmarketing, multi-institutional survey

Postmarketing data about the effectiveness of zonisamide in childhood epilepsy was collected from 759 children with various forms of epilepsy (ages 3 months-15 years) to compare the long-term efficacy of zonisamide in the treatment of epilepsy in intellectually normal versus intellectually disabled children. The follow-up period was 6 months-3 years; 291 children (245 intellectually normal, 46 ...

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Safety and Efficacy of Zonisamide in Patients with Epilepsy: A Post-Marketing Surveillance Study

BACKGROUND AND PURPOSE Zonisamide (ZNS) is one of new antiepileptic drug, which is known to inhibit seizure through multiple mechanisms of action. In Korea, ZNS was approved as an antiepileptic drug in 1992 and has been used for epilepsy patients with partial and generalized seizures. The objective of this study was to investigate the efficacy and tolerability of ZNS in patients with epilepsy a...

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Romiplostim can improve platelet counts in about 50% of patients with low- or intermediate 1-risk (lower risk) myelodysplastic syndromes (MDS) and thrombocytopenia, but its long-term toxicity and efficacy are not known. This open-label extension study evaluated the long-term safety and efficacy of romiplostim in 60 patients with lower risk MDS and platelet counts ≤50 × 109 /l. The primary endpo...

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ژورنال

عنوان ژورنال: Journal of Clinical Neurology

سال: 2007

ISSN: 1738-6586

DOI: 10.3988/jcn.2007.3.4.175